June 16, 2026 · Kidney international · DOI: 10.1016/j.kint.2026.05.013

A pilot study of magnetic resonance fingerprinting and radiomics analysis in autosomal dominant polycystic kidney disease

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This pilot study aimed to investigate whether radiomic features derived from magnetic resonance fingerprinting (MRF) can differentiate between children and young adults with autosomal dominant polycystic kidney disease (ADPKD) and healthy volunteers. The findings revealed that MRF-derived T1 and T2 relaxation times, along with selected radiomic features, significantly distinguished ADPKD patients from healthy individuals, highlighting the potential of MRF in detecting early changes in the non-cystic kidney parenchyma associated with the disease.

Linnea E Kremer, Madison E Kretzler, Christina J MacAskill, Jacob B Smothers, Chris A Flask, Katherine M Dell, Pottumarthi V Prasad, Mihai Giurcanu, Feng Li, Samuel G Armato, Arlene B Chapman

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