June 9, 2026 · JACC. Cardiovascular interventions · DOI: 10.1016/j.jcin.2026.04.012

Leaflet Modification for Redo-TAVR: Impact of Valve Type, Expansion, and Failure Mode-A Bench Study

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This study investigates the factors influencing the efficacy of leaflet modification techniques in redo transcatheter aortic valve replacement (TAVR), specifically examining how valve type, annular constraint, flow conditions, and leaflet degeneration affect outcomes. The authors found that leaflet splay varies significantly based on these factors, with different transcatheter heart valves responding uniquely to modification techniques. Overall, the results highlight the complexity of achieving effective leaflet modification in redo-TAVR procedures.

David Meier, Lucca Loretz, Edward Quine, Alison M Kane, David Elison, Brooke MacLeod, Colin Jamieson, Sheryl Munshan, Andrew Chatfield, Thomas Puehler, Nina Pommert, Gilbert H L Tang, Vasilis Babaliaros, Alessandro Beneduce, Arif A Khokhar, James M McCabe, John G Webb, Ole De Backer, David A Wood, Shinichi Fukuhara, Jaffar M Khan, Stephanie L Sellers

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