High-Dose Intravenous Vitamin C and Mortality and Organ Dysfunction in Severe Burn Injury: The VICTORY Randomized Clinical Trial
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The authors aimed to evaluate the efficacy of high-dose intravenous vitamin C in reducing mortality and organ dysfunction in patients with severe burn injuries. The randomized clinical trial found that vitamin C treatment did not improve 28-day mortality or persistent organ dysfunction and suggested potential harm, leading to early termination of the study. Specifically, the vitamin C group experienced higher mortality rates compared to the placebo group.
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