June 4, 2026 · BMJ (Clinical research ed.) · DOI: 10.1136/bmj-2025-088686

Systematic estimates of global causes of neonatal and under 5 mortality in 2000-24: secondary data analysis using bayesian multinomial logistic regression

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The authors aimed to estimate cause-specific mortality among neonates and children under five across 195 countries from 2000 to 2024 using a Bayesian multinomial logistic regression model. Their findings revealed that preterm birth complications were the leading cause of death, followed by lower respiratory infections and intrapartum-related events, while highlighting a concerning slowdown in the decline of under-five mortality rates since 2016. The study underscores the urgent need for targeted interventions in high mortality countries to meet sustainable development goals for child mortality.

Jamie Perin, David Prieto-Merino, Astha Wahi, Sandipan Pramanik, Hallie Eilerts-Spinelli, Francisco Villavicencio, Tyler H McCormick, Danzhen You, Abhirup Datta, Kathleen L Strong, Robert E Black, Li Liu

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