June 11, 2026 · BMJ (Clinical research ed.) · DOI: 10.1136/bmj-2025-086698

Low concentration atropine eye drops and progression of myopia in children: multicentre placebo controlled, double masked, randomised trial in the UK (CHAMP-UK)

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The study aimed to evaluate the efficacy and safety of low concentration atropine eye drops (0.01%) in reducing myopia progression in children aged 6-12 years in the UK. The results demonstrated that atropine significantly reduced myopia progression compared to placebo, with no serious adverse events reported, indicating it is a well-tolerated treatment option for managing myopia in this population.

Augusto Azuara-Blanco, Nicola S Logan, Emma McConnell, Stephanie Kearney, Gaynor Kirk, Susie Jones, Cliona McDowell, Lynn Murphy, Gerard O'Hanlon, Margaret McFarland, Sally Painter, Brinda Muthusamy, Shariar Nabili, Jennifer Preston, Ian Flitcroft, James Loughman, David Mackey, Samantha Lee, Annegret Dahlmann-Noor, Nathan Congdon, Ruth E Hogg, Chris J Hammond, Kathryn Saunders, Peter M Allen, Niall Strang, Mike Clarke

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