June 15, 2026 · BMJ (Clinical research ed.) · DOI: 10.1136/bmj-2025-084166

Advances in the development of malaria vaccines

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This review addresses the ongoing challenges in malaria elimination and examines recent advancements in vaccine development aimed at providing sustainable protection against *Plasmodium* species. The authors highlight the importance of targeting multiple stages of the parasite's life cycle and the need for innovative approaches, while also acknowledging the difficulties in identifying effective pre-erythrocytic antigens. They emphasize the necessity of integrating new technologies and enhancing vaccine delivery systems, particularly in high-burden regions like Africa, to improve current strategies and achieve malaria elimination.

Hermann Sorgho, Toussaint Rouamba, Hamtandi Magloire Natama, Halidou Tinto

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