May 9, 2026 · Gastroenterology · DOI: 10.1053/j.gastro.2026.04.027

Randomized Sham Controlled Trial of Translumbosacral Neuromodulation Therapy for Fecal Incontinence

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The authors aimed to evaluate the efficacy and safety of translumbosacral neuromodulation therapy (TNT) for treating fecal incontinence (FI) in a randomized sham-controlled trial. Results indicated that both 2400 and 3600 magnetic pulse treatments significantly reduced weekly FI episodes and improved bowel symptoms compared to sham treatment, with no serious adverse events reported, demonstrating that TNT is a promising non-invasive option for FI management.

Satish S C Rao, Yun Yan, Shaheen Hamdy, Kyle Staller, Karlo Fidel, Abeer Aziz, Amol Sharma, Jenna Clukey, Deepak Ayyala, Braden Kuo

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