Estrogen hormone therapy use in ovarian cancer patients under age 60 at diagnosis
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The authors aimed to investigate the impact of post-diagnosis estrogen hormone therapy (EHT) on survival rates among patients diagnosed with invasive epithelial ovarian cancer (EOC) before the age of 60. Their findings indicate that EHT is associated with improved survival in patients with high-grade serous and clear cell EOC, while it correlates with worse survival in those with endometrioid EOC, suggesting that EHT may be safely used for managing menopausal symptoms in certain EOC patients but requires caution in others. Further research is necessary to explore the effects of EHT on mucinous EOC survival.
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