May 6, 2026 · Gynecologic oncology · DOI: 10.1016/j.ygyno.2026.04.016

Impact of lymphadenectomy on survival outcomes for stage I malignant ovarian germ cell tumors

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The authors aimed to evaluate the impact of lymphadenectomy on survival outcomes in women with stage T1 malignant ovarian germ cell tumors (MOGCTs). Their analysis of data from the National Cancer Database revealed that while lymphadenectomy was associated with increased rates of adjuvant chemotherapy, it did not improve survival outcomes. The findings suggest that a more selective approach to lymphadenectomy may be warranted due to the low incidence of nodal metastasis and favorable survival rates in this patient population.

Delanie Ludmir, Yongmei Huang, Xiao Xu, Shayan Dioun, Alexander Buckley, Thomas Randall, Tarah Pua, Caryn M St Clair, June Y Hou, Koji Matsuo, Dawn L Hershman, Jason D Wright

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