Are patient factors associated with real-world antibody-drug conjugate outcomes in gynecologic cancers?
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The authors aimed to investigate whether patient demographic factors, such as age, race, and ethnicity, are associated with real-world outcomes of antibody-drug conjugates (ADCs) in patients with advanced gynecologic cancers. Their study found that while overall survival (OS) and progression-free survival (PFS) varied by ethnicity and performance status in unadjusted analyses, these differences were not significant after multivariable adjustment, suggesting that real-world ADC outcomes align with pivotal trial results and highlighting the need for further exploration of factors influencing treatment efficacy.
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