May 7, 2026 · Reproductive biology and endocrinology : RB&E · DOI: 10.1186/s12958-026-01545-w

Diverging guidelines and consensus statements on preimplantation genetic testing for aneuploidy: indications and strategies reviewed

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The authors aim to assess the consistency and standardization of preimplantation genetic testing for aneuploidy (PGT-A) practices by comparing recommendations from various authoritative guidelines and position statements. They identify both areas of consensus, such as advanced maternal age as a primary indication for PGT-A, and significant divergences in other indications and methodologies, highlighting the challenges posed by the rapid evolution of medical knowledge and the lack of robust evidence-based recommendations.

Laura Sichenze, Alexander Fiore, Maíra Casalechi, Edgardo Somigliana, Paola Viganò, Italian Society of Human Reproduction (SIRU)

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