May 1, 2026 · Reproductive biology and endocrinology : RB&E · DOI: 10.1186/s12958-026-01564-7

Endometriosis, subclinical cardiac remodeling, and cardiovascular risk: mechanistic insights from cardiac magnetic resonance and mediation analysis

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This study investigates the association between endometriosis and cardiovascular disease (CVD) risk, exploring the underlying mechanisms through cardiac magnetic resonance imaging and mediation analysis. The authors found that women with endometriosis have a significantly increased risk of CVD and early subclinical cardiac remodeling, primarily mediated by metabolic dysfunction and inflammation. These findings highlight the importance of cardiovascular risk assessment and metabolic monitoring in women diagnosed with endometriosis.

Yanzhi Feng, Kebing Nie, Mulun Xiao, Xingyu Liu, Tong Wu, Jinjin Zhang, Shixuan Wang

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