May 6, 2026 · Journal of addiction medicine · DOI: 10.1097/ADM.0000000000001706

From Management to Maintenance: A Pilot Ambulatory Gabapentin Bridge Protocol for Treatment of Low-risk Alcohol Withdrawal Syndrome

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The authors aimed to evaluate the safety and effectiveness of a fixed-dose gabapentin taper protocol for managing low-risk alcohol withdrawal syndrome (AWS) in an ambulatory setting. Their pilot study of 10 patients showed no progression to complicated withdrawal, high rates of short-term abstinence, and successful transitions to maintenance pharmacotherapy for alcohol use disorder. The findings suggest that this gabapentin protocol may be a viable alternative to traditional treatment methods, warranting further investigation through randomized trials.

Samata R Sharma, Kate Takayoshi, Rachel Hardenstine, Joji Suzuki

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