May 6, 2026 · Journal of addiction medicine · DOI: 10.1097/ADM.0000000000001638

Maternal Opioid-related Diagnosis in Pregnancy and Risk of Adverse Perinatal Outcomes

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The authors aimed to investigate the relationship between opioid-related diagnoses during pregnancy and subsequent maternal and neonatal outcomes using a large, diverse cohort from California. Their findings reveal that opioid-related diagnoses have more than doubled from 2008 to 2020 and are significantly linked to increased risks of severe maternal morbidity and various adverse neonatal outcomes, including higher rates of infant death and neonatal abstinence syndrome.

Kristin C Prewitt, Kimberly S Ryan, Bharti Garg, Sarena Hayer, Olivia L Hagen, Elinor L Sullivan, Aaron B Caughey, Ashley E Benson, Jamie O Lo

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