May 5, 2026 · Radiology · DOI: 10.1148/radiol.251347

Associations of MRI-derived Paraspinal IMAT and LMM with Cardiometabolic Risk Factors: Results from a German Cohort

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The authors aimed to investigate the independent and combined associations of intermuscular adipose tissue (IMAT) and lean muscle mass (LMM) with cardiometabolic risk factors in individuals without pre-existing conditions. Their findings revealed that increased IMAT was linked to higher odds of hypertension and dyslipidemia, while greater LMM was associated with lower odds of these risk factors, particularly in men. Overall, the study highlights the significance of IMAT and LMM in assessing cardiometabolic health in a healthy population.

Sebastian Ziegelmayer, Hartmut Häntze, Christian Mertens, Felix Busch, Tristan Lemke, Markus Graf, Nassir Navab, Shahrooz Faghihroohi, Jakob Nikolas Kather, Daniel Truhn, Thomas Kröncke, Jacqueline Lammert, Su Hwan Kim, Benedikt Wiestler, Jeanette Schulz-Menger, Annette Peters, Henry Völzke, Robin Bülow, Thoralf Niendorf, Hans-Ulrich Kauczor, Tobias Nonnenmacher, Tobias Pischon, Steffen Ringhof, Christopher L Schlett, Jakob Weiß, Fabian Bamberg, Ulrike Streit, Martin Hadamitzky, Marcus R Makowski, Lisa Adams, Keno Bressem

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