Quantitative Phase-resolved Functional Lung MRI Prediction of Disease Progression in Connective Tissue Disease-associated Interstitial Lung Disease

The authors aimed to investigate whether ventilation and perfusion parameters quantified through phase-resolved functional lung (PREFUL) MRI can predict disease progression in patients with connective tissue disease-associated interstitial lung disease (CTD-ILD). Their findings indicate that distinct pulmonary perfusion phenotypes identified by PREFUL MRI correlate with disease progression over one year, demonstrating the potential of these functional parameters in guiding clinical management of CTD-ILD.