May 4, 2026 · JAMA · DOI: 10.1001/jama.2026.6070

Hepatitis B: A Review

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This review examines the global impact of hepatitis B virus (HBV) infection, which affects approximately 254 million people and leads to about 1.1 million deaths annually. The authors aim to highlight effective prevention strategies, such as universal birth-dose vaccination and antiviral therapies, which significantly reduce perinatal transmission and the progression of chronic HBV infection to severe liver complications. The findings underscore the importance of vaccination and timely treatment in mitigating the health burden of HBV.

Wen-Juei Jeng, Terry Cheuk-Fung Yip, Anna S Lok

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