April 28, 2026 · Gut · DOI: 10.1136/gutjnl-2026-338223

Metagenomic identification of gut microbiome signatures for accurate diagnosis and prognostic prediction of Epstein-Barr virus-associated nasopharyngeal carcinoma

Listen to this summary

The authors aimed to investigate the relationship between gut microbiome alterations and Epstein-Barr virus (EBV)-associated nasopharyngeal carcinoma (NPC) to enhance diagnostic and prognostic capabilities. Their findings revealed significant dysbiosis in the gut microbiome of NPC patients, with specific microbial species correlating with EBV DNA levels and patient mortality. The study demonstrates that microbiome-based diagnostic tools, especially when combined with EBV markers, show strong potential for improving NPC diagnosis and understanding its association with an immune-suppressive tumor microenvironment.

Kaiqi Lan, Defeng Bai, Li Yuan, Hao Luo, Jing Jin, Su-Chen Li, Lin-Fang Wu, Xue-Song Sun, Sai-Lan Liu, Qiu-Yan Chen, Hai-Qiang Mai, Yong-Xin Liu, Lin-Quan Tang

This is one of 33,000+ journals available on OSLR. Try it free for 14 days.

Free 14-day trial. 33,000+ journals. Cancel anytime.

14-day free trial. No commitment.

"Oslr has become part of my weekly routine on my day off. The clinical relevance of the summaries is outstanding — I'd rate it 9/10. Being able to consume research hands-free is a huge advantage for busy physicians."

Dr. Jennifer Thompson

Dr. Jennifer Thompson

Portland, OR

Stay current without falling behind

33,000+ journals. 3-minute audio summaries. Free for 14 days.

Download on the App StoreGet it on Google Play