Genetic determinants of childhood blood pressure and heart rate in relation to adult health outcomes: the consortium of childhood blood pressure
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The authors aimed to elucidate the genetic determinants of childhood blood pressure (BP) and heart rate (HR) and their potential implications for adult health outcomes. Through the largest genome-wide association study of its kind, they identified several novel genetic loci associated with childhood BP and HR, revealing moderate genetic correlations with adult BP traits. Their findings suggest that higher childhood BP genetic risk scores are linked to increased risks of various cardiometabolic conditions in adulthood, highlighting the importance of early interventions.
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