April 25, 2026 · Gynecologic oncology · DOI: 10.1016/j.ygyno.2026.04.009

Predictive features of anastomotic leakage after colorectal resection in complex multivisceral cytoreductive surgery for ovarian cancer

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The authors aimed to identify preoperative and intraoperative predictive features of colorectal anastomotic leakage (AL) in patients undergoing complex cytoreductive surgery for ovarian cancer. They found that a lymphocyte-to-monocyte ratio ≥ 2.14 was associated with a lower likelihood of AL, while extensive pelvic disease and concurrent splenectomy were strong predictors of AL. Although AL led to longer hospital stays and higher re-intervention rates, it did not significantly impact disease-free or overall survival.

Luca Sorrentino, Giorgio Bogani, Valentina Chiappa, Luca Lalli, Lorenzo Ceppi, Simone Bruni, Umberto Leone Roberti Maggiore, Francesco Raspagliesi

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