April 23, 2026 · Critical care medicine · DOI: 10.1097/CCM.0000000000007130

Effects of Early Versus Delayed Mechanical Thrombectomy on Outcomes in Intermediate-Risk Acute Pulmonary Embolism

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The authors aimed to determine whether the timing of mechanical thrombectomy (early vs. delayed) affects clinical outcomes, particularly in-hospital mortality, in patients with intermediate-risk pulmonary embolism (PE). Their findings indicated that while the timing of intervention did not significantly impact mortality rates, early intervention was associated with greater reductions in pulmonary artery pressures and lower rates of intubation compared to delayed intervention.

Caleb J Chiang, Kelsey E Bria, Pavlina Chrysafi, Virginia Falvello, Kristen M Sanfilippo, Jordan K Schaefer, Kenneth Bauer, Rushad Patell, Lisa Baumann Kreuziger, Rebecca L Freese, Alejandra Gutierrez Bernal

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