April 8, 2026 · Critical care medicine · DOI: 10.1097/CCM.0000000000007131

The Influence of Older Age on RBC Transfusion Decisions in ICU Patients

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This study investigates how age influences red blood cell (RBC) transfusion practices in ICU patients, particularly focusing on whether older patients receive different transfusion strategies compared to younger ones. The findings reveal that while patients over 85 years have higher hemoglobin thresholds and cite age-related reasons for transfusion, age itself does not significantly affect the likelihood of receiving an RBC transfusion after adjustments. Thus, the observed differences in transfusion practices appear to be more related to physiological and diagnostic factors rather than age alone.

Caroline M Schaap, Senta Jorinde Raasveld, Florian Reizine, Boillot Corentin, Jimmy Schenk, Sanne de Bruin, Merijn C Reuland, Claudia van den Oord, Andrew W J Flint, Tarikul Hamid, Michaël Piagnerelli, Tina Tomić Mahečić, Jan Benes, Lene Russell, Hernan Aguirre-Bermeo, Konstantina Triantafyllopoulou, Vasiliki Chantziara, Mohan Gurjar, Sheila Nainan Myatra, Vincenzo Pota, Muhammed Elhadi, Ryszard Gawda, Mafalda Mourisco, Marcus Lance, Vojislava Neskovic, Matej Podbregar, Juan V Llau, Manual Quintana-Diaz, Maria Cronhjort, Carmen A Pfortmueller, Nihan Yapici, Nathan Nielsen, Akshay Shah, Jan Bakker, Maurizio Cecconi, Aarne Feldheiser, Jens Meier, Zoe McQuilten, Marcella C A Müller, Thomas W L Scheeren, Cécile Aubron, Alexander P J Vlaar, Harm-Jan de Grooth, International Point Prevalence Study of ICU Transfusion Practices (InPUT) study group

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