Proton beam therapy for oropharyngeal cancer (TORPEdO): a phase 3, randomised controlled trial
Listen to this summary
The authors conducted a phase 3 trial (TORPEdO) to compare the clinical benefits of intensity-modulated proton therapy (IMPT) versus intensity-modulated radiation therapy (IMRT) in patients with locally advanced oropharyngeal squamous cell carcinoma, specifically assessing treatment-related effects on physical function and quality of life. The results indicated that both treatment modalities yielded similar outcomes regarding late physical quality of life, gastrostomy-tube dependence, disease control, and overall survival, suggesting that IMRT remains the standard of care in settings where IMPT is not routinely utilized.
This is one of 33,000+ journals available on OSLR. Try it free for 14 days.
Free 14-day trial. 33,000+ journals. Cancel anytime.
More from Lancet (London, England)
View all →Mar 23, 2026 · Lancet (London, England)
Primary sclerosing cholangitis
Mar 22, 2026 · Lancet (London, England)
Efficacy and safety of oral semaglutide 14 mg (flexible dose) in early-stage symptomatic Alzheimer's disease (evoke and evoke+): two phase 3, randomised, placebo-controlled trials
Mar 21, 2026 · Lancet (London, England)
Survival outcome of VATS compared with open lobectomy for lung cancer: an individual patient data meta-analysis of randomised trials
Mar 21, 2026 · Lancet (London, England)
Angiography-derived fractional flow reserve versus coronary angiography to guide coronary artery bypass grafting in patients undergoing surgical valve procedures with concomitant coronary artery disease in China (FAVOR IV-QVAS): a multicentre, triple-blind, randomised trial
Mar 21, 2026 · Lancet (London, England)
Prevention of urinary stones with hydration: a randomised clinical trial of an adherence intervention
Mar 19, 2026 · Lancet (London, England)
More equitable preconception health: paternal life course opportunities for better pregnancy, child, and family outcomes
More in Nuclear Medicine
View all →Mar 25, 2026 · The New England journal of medicine
A Placebo-Controlled Trial of the Oral PCSK9 Inhibitor Enlicitide
Mar 23, 2026 · The New England journal of medicine
The Inherited Basis of Coronary Artery Disease
Mar 18, 2026 · The New England journal of medicine
Left Atrial Appendage Closure or Medical Therapy in Atrial Fibrillation
Mar 17, 2026 · The New England journal of medicine
Prehospital Whole Blood in Traumatic Hemorrhage - a Randomized Controlled Trial
Mar 17, 2026 · The New England journal of medicine
High-Flow or Standard Oxygen in Acute Hypoxemic Respiratory Failure
Mar 11, 2026 · The New England journal of medicine
Polymyalgia Rheumatica
"Oslr has become part of my weekly routine on my day off. The clinical relevance of the summaries is outstanding — I'd rate it 9/10. Being able to consume research hands-free is a huge advantage for busy physicians."
Dr. Jennifer Thompson
Portland, OR
Stay current without falling behind
33,000+ journals. 3-minute audio summaries. Free for 14 days.
