Immune checkpoint inhibitor-associated inflammatory arthritis
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The authors aim to elucidate the mechanisms underlying immune checkpoint inhibitor-associated inflammatory arthritis (ICI-IA), which occurs in approximately 6% of patients receiving ICI cancer therapy and resembles rheumatoid arthritis. They discuss the cellular characteristics of ICI-IA, including the role of specific T cell and macrophage populations, and suggest that understanding ICI-IA may provide insights into the biology of other inflammatory arthritis forms. The review highlights current knowledge and proposes future research directions in this area.
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