September 21, 2026 · Journal of the American College of Radiology : JACR · DOI: 10.1016/j.jacr.2026.09.013

Opportunistic Screening for Cardiovascular and Chronic Obstructive Pulmonary Disease Biomarkers and Implications for Downstream Care: A Retrospective Lung Cancer Screening Cohort Study

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The authors aimed to investigate the prevalence of cardiovascular disease (CVD) and chronic obstructive pulmonary disease (COPD) biomarkers in asymptomatic lung cancer screening participants and their implications for subsequent healthcare. They found that a significant percentage of participants had emphysema (76.7%) and coronary artery calcium (CAC) (65.1%), with both conditions linked to increased cardiopulmonary care following low-dose CT screening. Additionally, social determinants of health, such as income and food insecurity, were associated with the prevalence of emphysema, highlighting the need for equitable healthcare pathways.

Lauren K Groner, Maria Patricia Puello, Chukwuma Onyebeke, Charlene Thomas, Valentina Marulanda Corzo, Tashina Andrade, Hanna Haile, Anthony Saleh, Jessica M Pena, Daniel B Green, Laura C Pinheiro

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