Prospective Shadow-Mode Evaluation of an Artificial Intelligence Tool for Intracranial Aneurysm Detection on CT Angiography: Incremental Yield and Operational Impact

The authors aimed to evaluate the operational performance of an FDA-cleared artificial intelligence (AI) algorithm for detecting intracranial aneurysms in brain CT angiography (CTA) and to assess the added value of combining AI with radiologist assessments. The study found that the AI demonstrated higher sensitivity than radiologists alone, identified additional aneurysms, and showed favorable operational metrics, particularly in inpatient settings, suggesting its potential for effective integration into clinical practice.