September 20, 2026 · Heart rhythm · DOI: 10.1016/j.hrthm.2026.09.004

STAR Apollo™ Map-Guided Redo Ablation for Recurrent Persistent Atrial Fibrillation after Prior Pulmonary Vein Isolation: Procedural Feasibility, Safety, and Twelve-Month Rhythm Outcomes from a Prospective Multicenter Study (NCT05826665)

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The authors aimed to evaluate the procedural feasibility, safety, and 12-month rhythm outcomes of STAR Apollo™ Map-guided redo ablation in patients with recurrent persistent atrial fibrillation (AF) following prior pulmonary vein isolation (PVI). The study found that the procedure was feasible and safe, with a significant proportion of patients achieving sinus rhythm and symptom improvement at 12 months. However, the authors note that the study's design limits the ability to establish the incremental efficacy of STAR guidance compared to standard PVI re-isolation.

Rajesh Kabra, Matthew McKillop, Aaditya Vora, Saumil Oza, Devi G Nair, Dilip Mathew, Douglas Darden, Dhanunjaya R Lakkireddy, STAR Apollo Study Investigators

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