Heart rhythm
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Arrhythmias in d-Transposition of the great arteries after Mustard- or Senning-type atrial redirection surgery - 22 years of experience in catheter ablation and follow-up

Aug 6, 2026

The authors aimed to evaluate the effectiveness and long-term outcomes of catheter ablation for atrial tachyarrhythmias in patients with d-transposition of the great arteries (d-TGA) who underwent Mustard or Senning atrial redirection surgery. Their findings indicate that catheter ablation is both feasible and highly effective, with an acute success rate of 86%, but also reveal a significant incidence of new arrhythmias over time, particularly in patients who had Mustard surgery. This highlights the ongoing risk of arrhythmias in this population and the need for tailored long-term management strategies.

Association of Angiotensin Receptor Neprilysin Inhibitors Duration with Latent Remodeling Following Implantable Cardioverter Defibrillator Implantation

Aug 6, 2026

This study aimed to investigate the relationship between the duration of angiotensin receptor neprilysin inhibitor (ARNI) therapy prior to implantable cardioverter defibrillator (ICD) implantation and latent left ventricular reverse remodeling (LVRR) in patients with nonischemic dilated cardiomyopathy (NIDCM). The findings indicated that shorter durations from heart failure diagnosis and ARNI initiation to ICD implantation were independently associated with a higher likelihood of latent LVRR, suggesting the importance of adequate guideline-directed medical therapy for optimizing cardiac remodeling while managing arrhythmic risks.

Body mass index, acute atrial fibrillation termination, and long-term recurrence after catheter ablation for persistent atrial fibrillation: insights from a large contemporary cohort

Aug 5, 2026

The authors aimed to investigate the relationship between body mass index (BMI) and both the acute termination of atrial fibrillation (AF) and the long-term recurrence of atrial arrhythmia following catheter ablation for persistent AF. They found that higher BMI was associated with lower rates of acute AF termination and increased risks of long-term recurrence, suggesting that BMI could be a valuable marker for preprocedural risk assessment in patients undergoing this treatment.

Association of early rhythm control with depression outcomes in atrial fibrillation: A nationwide population-based cohort study

Aug 4, 2026

This study investigates the impact of early rhythm control (ERC) on the onset and worsening of depression in patients with atrial fibrillation (AF). Analyzing a large cohort, the authors found that ERC is associated with a reduced risk of new-onset depression in patients without prior depression and lower rates of hospital admissions for depression-related issues in those with a history of depression. The findings suggest that implementing ERC may have beneficial effects on mental health outcomes in AF patients.

Hemolysis and Renal Tubular Injury After Pulsed Field Ablation: A Comparison Between Two Commercially Available Platforms

Aug 4, 2026

The authors aimed to investigate whether the differences in hemolysis caused by two commercially available pulsed field ablation (PFA) platforms, PulseSelect and Farapulse, would result in varying degrees of renal tubular injury. Their findings revealed that while Farapulse induced greater hemolysis, as indicated by significant changes in hemolysis markers, there were no corresponding differences in urinary tubular injury biomarkers or renal function between the two platforms. Thus, the study concludes that the increased hemolytic response associated with Farapulse does not lead to detectable renal tubular injury in the studied patient population.

THERMAL PROFILES OF PULSED FIELD ABLATION CATHETERS

Aug 4, 2026

The authors aimed to characterize the thermal profiles and peak surface temperatures of six proprietary pulsed field ablation (PFA) catheters using an ex vivo model. Their findings revealed distinct thermal signatures among the catheters, with varying degrees of temperature rise and patterns of heating, which are crucial for understanding the efficacy and safety of PFA in clinical applications. The study categorizes the catheters into low, moderate, and high heating profiles based on their thermal responses.

Sampling Frequency Has Architecture-Dependent Effects on ECG Deep Learning Classification: CNNs Are Robust, Transformers Benefit Modestly

Aug 4, 2026

This study investigates how varying ECG sampling frequencies (100, 300, and 500 Hz) affect the classification performance and computational costs of convolutional neural networks (CNNs) and Patch Transformers. The results indicate that CNNs maintain stable performance across different frequencies, while Patch Transformers show modest improvements with higher frequencies but at increased computational costs. The findings suggest that ECG acquisition strategies should consider both the task requirements and the architecture used, especially in resource-limited environments.

Output-Dependent Electrocardiographic Criteria to Distinguish Bachmann Bundle Area Pacing from High Atrial Septal Pacing: Validation with Coronary Sinus Mapping

Aug 3, 2026

The authors aimed to determine if output-dependent electrocardiographic changes could effectively differentiate Bachmann bundle area pacing (BBAP) from high atrial septal pacing (HASP) during implantation, given their anatomical overlap. Through a study of 57 patients, they found that specific changes in P-wave morphology and timing correlated with successful identification of BBAP, suggesting these ECG markers could serve as practical indicators of preferential interatrial conduction. The study highlights the potential for these findings to inform pacing strategies, although further validation is needed.

Atrial Fibrillation in Transthyretin Amyloid Cardiomyopathy: Mechanisms, Prognostic Implications, and Management

Aug 3, 2026

The authors investigate the prevalence and management of atrial fibrillation (AF) in patients with transthyretin amyloid cardiomyopathy (ATTR-CM), noting that AF occurs in over 70% of these patients and often precedes the diagnosis of cardiomyopathy. They highlight the unique challenges in managing AF due to the disease's effects on atrial structure and function, advocating for early rhythm control and considering catheter ablation as a promising option for select patients. The review emphasizes the importance of optimizing AF management as new therapies improve overall survival in ATTR-CM.

Different Renal Function Estimation Formulas for Adverse Outcomes in Patients with Atrial Fibrillation Receiving Direct Oral Anticoagulants

Aug 3, 2026

The authors aimed to compare the concordance and predictive performance of various renal function estimation formulas in relation to adverse clinical outcomes in patients with atrial fibrillation receiving direct oral anticoagulants. Their findings indicate that while most patients were classified as having normal renal function, the Cockcroft-Gault formula outperformed other formulas in predicting major adverse events, highlighting its importance in managing these patients.