September 18, 2026 · The American journal of emergency medicine · DOI: 10.1016/j.ajem.2026.09.021

Severe atomoxetine overdose presenting with status epilepticus and wide-complex ventricular tachycardia

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This case report investigates the severe effects of atomoxetine overdose, specifically addressing the neurological and cardiovascular complications that can arise from high doses. The authors detail the presentation of a 21-year-old woman who experienced status epilepticus, metabolic acidosis, and wide-complex ventricular tachycardia following a massive overdose, highlighting critical management strategies such as airway protection and sodium bicarbonate therapy. The findings underscore the potential for life-threatening toxicity in severe atomoxetine overdoses and the importance of prompt medical intervention.

Ryoko Kyan, Takuyo Chiba, Masatoshi Miyamoto, Hiroko Abe, Tomohisa Nagayama, Yusuke Naito, Yoshito Kamijo

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