Intracoronary Imaging-Guided Percutaneous Coronary Intervention: An Updated Meta-Analysis of Randomized Trials
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The authors aimed to re-evaluate the efficacy of intracoronary imaging (ICI)-guided percutaneous coronary intervention (PCI) compared to angiography-guided PCI, particularly in light of recent trials showing no benefit. Their updated meta-analysis of 28 randomized controlled trials involving over 24,000 patients found that ICI-guided PCI significantly reduced various cardiovascular events, including target lesion failure and cardiac mortality, while also revealing geographic and lesion characteristic heterogeneity as key factors influencing trial outcomes.
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