A Synopsis of the 2025 U.S. Department of Veterans Affairs and U.S. Department of Defense Clinical Practice Guideline for Lipid Management for Cardiovascular Disease Risk Reduction
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The authors review the 2025 updates to the U.S. Department of Veterans Affairs and Department of Defense clinical practice guideline for lipid management aimed at reducing cardiovascular disease risk. They address key questions regarding lipid management strategies, highlighting new recommendations such as the use of the PREVENT calculator for risk estimation, the inclusion of coronary artery calcium testing, and the endorsement of moderate-intensity statins for various patient populations, including those living with HIV. The update emphasizes a shift towards more intensive lipid-lowering therapies, particularly for high-risk patients.
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