Mortality Effect of Peripheral Perfusion-Guided Resuscitation in Vasodilatory Shock: A Systematic Review and Dual Frequentist-Bayesian Meta-Analysis of Randomized Trials
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The authors aimed to evaluate the impact of peripheral perfusion-guided resuscitation on 28-day mortality in adults experiencing vasodilatory shock. Their systematic review and meta-analysis of seven randomized controlled trials found a pooled risk ratio suggesting a potential reduction in mortality, although this did not reach statistical significance. The Bayesian analysis indicated a high probability that the intervention may be beneficial, highlighting the need for further adequately powered studies to clarify its clinical significance.
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