September 11, 2026 · Climacteric : the journal of the International Menopause Society · DOI: 10.1080/13697137.2026.2715247

Perimenopausal symptom burden: implications for health, work and earlier clinical management

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This study investigates the symptom burden, health-related quality of life (HRQoL), and work-related outcomes in perimenopausal women, aiming to highlight the need for improved clinical attention during reproductive aging. The findings reveal that symptom severity significantly increases with age and menstrual status, particularly in women with irregular cycles and those who are postmenopausal, leading to lower HRQoL and job satisfaction. The authors suggest that recognizing these issues earlier could guide more effective, stage-specific clinical management.

Doris Rodríguez-Vidal, Juan E Blümel, Peter Chedraui, María S Vallejo, Lucia Costa-Paiva, Hugo Gutiérrez-Crespo, Maribel Dextre, Karen Díaz, Alejandra Elizalde-Cremonte, Santiago Elizalde-Cremonte, Carlos Escalante-Gómez, María T Espinoza, Ircania García, Gustavo Gómez-Tabares, Juan Matzumura-Kasano, Paolo Meza, Álvaro Monterrosa-Castro, Mónica Ñañez, Marcela López, Eliana Ojeda, Claudia Rey, Ana Lucia Ribeiro Valadares, Marcio A H Rodrigues, Javier Saavedra, Carlos Salinas, Lida Sosa, Konstantinos Tserotas, Margot Acuña-San Martín, Sócrates Aedo, Marcela S Aguirre, Eugenio Arteaga, Félix Ayala, Ascanio Bencosme, Andrés Calle

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