September 2, 2026 · BMJ (Clinical research ed.) · DOI: 10.1136/bmj-2026-100460

Secondary use and scholarly impact of a portfolio of clinical trials with shared individual participant level data: cross sectional study

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The authors aimed to evaluate the number, characteristics, and scholarly impact of secondary publications derived from individual participant level data (IPD) shared through the Yale University Open Data Access (YODA) Project platform. They found that a significant majority of clinical trials generated secondary publications, with external investigators increasingly contributing to this body of work over time. The study highlights the potential of structured data sharing to enhance the scientific value of clinical trials, as external publications were often of higher journal impact but had lower citation counts compared to internal publications.

Erfan Taherifard, Maryam Mooghali, Hollin R Hakimian, Sahil R Mane, Mengyuan Fu, Stephen Bamford, Jesse A Berlin, Karla Childers, Nihar R Desai, Cary P Gross, Debbie Hewens, Richard Lehman, Jessica D Ritchie, Tamsin Sargood, Joanne Waldstreicher, Joshua D Wallach, Molly K Willeford, Harlan M Krumholz, Joseph S Ross

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