August 28, 2026 · BMJ (Clinical research ed.) · DOI: 10.1136/bmj-2026-635470

Schizophrenia: advances in pathophysiology, management, and precision medicine

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The authors investigate the complex pathophysiology of schizophrenia and the challenges in its management, highlighting the need for precision medicine approaches that consider the biological heterogeneity of patients. They emphasize the importance of identifying objective biomarkers to facilitate patient stratification and improve therapeutic strategies, while also discussing the potential of both biological and non-biological interventions in enhancing treatment outcomes.

Akira Sawa, Joshua Chiappelli, Olivia P Hamrah, Nicola G Cascella

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