Global Prevalence of Celiac Disease and Clinical Characteristics in the General Population: A Systematic Review and Meta-analysis
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The authors aimed to update the global prevalence estimates of celiac disease (CeD) and characterize its clinical features, as well as assess the impact of diagnostic methods on detection rates. Their systematic review and meta-analysis of 87 studies revealed a global seroprevalence of 1.5% and a biopsy-confirmed prevalence of 0.8%, with significant variations based on demographics and diagnostic approaches. Notably, around 41% of biopsy-confirmed patients were asymptomatic, underscoring the need for improved detection strategies worldwide.
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