July 30, 2026 · JAMA · DOI: 10.1001/jama.2026.13087

Nicotine E-Cigarettes for Cigarette Smoking Cessation: Recommendations to US-Based Clinicians

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The authors aim to address how clinicians can effectively integrate e-cigarettes into smoking cessation discussions with patients, given their potential benefits compared to traditional nicotine replacement therapies. They provide evidence-based recommendations for engaging patients in shared decision-making about the risks and benefits of e-cigarettes, while also clarifying common misconceptions about their safety. Ultimately, the paper advocates for the inclusion of e-cigarettes as a viable option in pharmacologic treatments for smoking cessation to mitigate the health risks associated with cigarette smoking.

Eleanor L S Leavens, Kinsey Pebley, Tracy T Smith, Jasjit S Ahluwalia, Mariel S Bello, Krysten W Bold, Jennifer Cantrell, Matthew J Carpenter, Patricia A Cioe, Nicholas J Felicione, Alys Havard, Larry W Hawk, Jesse T Kaye, Elias M Klemperer, Bethea A Kleykamp, Nicola Lindson, Erin A McClure, Hayden McRobbie, Cara M Murphy, Nancy A Rigotti, Natalie K Walker, Min-Jeong Yang, Alana M Rojewski, Adrienne L Johnson, Members of the Society for Research on Nicotine and Tobacco, Treatment Research Network, Harm Reduction Workgroup

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