Harnessing the Biologic Power of Bacteriophages to Improve the Treatment of Periprosthetic Joint Infection: Barriers and Future Directions
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The authors investigate the potential of bacteriophage therapy as an adjunct treatment for periprosthetic joint infection (PJI), which has high failure rates with current therapies. They aim to address the barriers to integrating phage therapy into clinical practice, particularly the knowledge gap between preclinical research and its application in standard care. The review outlines the therapeutic advantages of phages while identifying ongoing challenges that hinder their adoption in treating PJI.
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