July 23, 2026 · Journal of the American College of Radiology : JACR · DOI: 10.1016/j.jacr.2026.07.011

Clinical Management and Outcomes Based on Functional CAD-RADS Compared to Anatomical CAD-RADS in Patients with Stable Coronary Artery Disease

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This study investigates whether the novel functional CAD-RADS, which incorporates CT-derived fractional flow reserve (CT-FFR), provides better prognostic value for predicting major adverse cardiac events (MACE) compared to the traditional anatomical CAD-RADS in patients with stable coronary artery disease. The findings indicate that functional CAD-RADS not only predicts MACE more accurately but also leads to fewer inappropriate management decisions, suggesting its potential clinical utility in guiding treatment strategies for patients with intermediate stenosis.

Chun Xiang Tang, Fan Zhou, Hong Yan Qiao, U Joseph Schoepf, Tong Yuan Liu, Ya Liu, Long Jiang Zhang

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