July 21, 2026 · BMC women's health · DOI: 10.1186/s12905-026-04714-6

Association of vaginal dysbiosis with cervical lesions among women with non-16/18 high-risk HPV infections: a cross-sectional study of 2,264 women in Eastern China

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The authors aimed to investigate the association between vaginal dysbiosis and the risk of cervical lesions in women infected with non-16/18 high-risk HPV genotypes. Their cross-sectional study of 2,264 women found that while vaginal dysbiosis was linked to cervical lesions, particularly with HPV58 and HPV59, the results did not reach statistical significance for multiplicative interactions. The findings are exploratory and suggest the need for further prospective studies to validate these associations before considering changes to cervical cancer screening practices.

Shuying Yuan, Dan Wu, Kexin Hu, Yongxinag Li

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