July 21, 2026 · BMC women's health · DOI: 10.1186/s12905-026-04698-3

Comparison of vaginal natural orifice transluminal endoscopic surgery and multiport conventional laparoscopy for complete pelvic lymphadenectomy: Insights from a single-surgeon experience

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The authors aimed to compare the outcomes of complete pelvic lymphadenectomy performed via vaginal natural orifice transluminal endoscopic surgery (vNOTES) versus multiport conventional laparoscopy (MCL) in patients with endometrial cancer after unsuccessful sentinel lymph node mapping. They found that while vNOTES resulted in significantly lower postoperative pain and improved recovery scores, it also had longer operative times compared to MCL, with no significant differences in blood loss or lymph node yield. The study suggests that vNOTES may offer advantages in terms of pain and recovery, but further research is needed to confirm these findings and assess long-term oncologic outcomes.

Kemal Gungorduk, Serkan Ustuntas, Emre Biton, Berican Sahin Uyar, Berke Nur Ergu, Furkan Karaoz, Varol Gulseren, Munteha Akbulut, Berfin Akan Isler

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