July 20, 2026 · Circulation · DOI: 10.1161/CIRCULATIONAHA.126.079275

Diagnostic Approach to Cardiac Sarcoidosis

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The authors aim to address the challenges in diagnosing cardiac sarcoidosis, a condition associated with significant cardiovascular risks, by organizing a diagnostic approach based on clinical contexts. They highlight the limitations of current diagnostic modalities and consensus guidelines, proposing a 5-step pathway that incorporates advanced imaging, tissue acquisition, and genetic evaluation to improve diagnostic accuracy. The paper emphasizes the need for further validation of diagnostic strategies, particularly for isolated cardiac sarcoidosis.

Jukka Lehtonen, David H Birnie

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