Adjuvant Chemotherapy ± Chemoradiotherapy for Adenocarcinoma of the Pancreatic Head: Results of the Radiotherapy Random Assignment of NRG Oncology/RTOG 0848
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The authors aimed to determine whether adding fluoropyrimidine sensitized radiotherapy (CXRT) to adjuvant chemotherapy improves overall survival (OS) in patients with adenocarcinoma of the pancreatic head after curative resection. The study found that while CXRT did not significantly enhance OS or disease-free survival (DFS) for the overall population, it showed a beneficial effect on OS and DFS in node-negative patients, suggesting a potential role for CXRT in this subgroup.
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