July 9, 2026 · European heart journal · DOI: 10.1093/eurheartj/ehag517

Transformer-based models for predicting cardiovascular risk in Chinese adults: development and validation

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The authors aimed to develop and validate transformer-based models, named China-AIHeart, for predicting 10-year cardiovascular disease (CVD) risk in Chinese adults, addressing the limitations of traditional Cox proportional hazards models. Their study demonstrated that these models significantly outperformed Cox models and established risk scores in terms of discrimination and calibration, providing a robust tool for CVD risk stratification in this population. External validation confirmed the models' effectiveness across different cohorts, highlighting their practical applicability in clinical settings.

Qiuyu Cao, Xingkun Xu, Hong Lin, Yue Yin, Shengli Wu, Mian Li, Yu Xu, Shaoxin Li, Yuchen Xu, Huapeng Wei, Ruizhi Zheng, Yujing Zhu, Min Xu, Tiange Wang, Zhiyun Zhao, Yiming Mu, Lulu Chen, Tianshu Zeng, Lixin Shi, Qing Su, Xuefeng Yu, Li Yan, Guijun Qin, Qin Wan, Gang Chen, Xulei Tang, Zhengnan Gao, Ruying Hu, Zuojie Luo, Yingfen Qin, Li Chen, Xinguo Hou, Yanan Huo, Qiang Li, Guixia Wang, Yinfei Zhang, Chao Liu, Youmin Wang, Feixia Shen, Xuejiang Gu, Tao Yang, Huacong Deng, Yifang Zhang, Jiajun Zhao, Guang Ning, Feiyue Huang, Weiqing Wang, Yufang Bi, Jieli Lu

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