Use of Cystatin C in Tandem with Creatinine to Improve GFR Estimation and Clinical Decision Making
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The authors investigate the potential benefits of incorporating cystatin C alongside serum creatinine for estimating glomerular filtration rate (GFR) and improving clinical decision-making in chronic kidney disease (CKD) management. They highlight that cystatin C-inclusive equations generally provide better accuracy and prognostic value for various clinical outcomes compared to creatinine-only equations, particularly in diverse patient populations. The paper also addresses the barriers to widespread clinical adoption of cystatin C and suggests strategies for its implementation in healthcare systems.
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