Donor Urinary Biomarkers and the Prediction of Deceased Donor Allograft Function

The authors aimed to determine whether incorporating donor urinary biomarkers alongside the Kidney Donor Profile Index (KDPI) could enhance the prediction of allograft outcomes in kidney transplantation. Their findings indicate that the combination of KDPI with urinary biomarkers such as uromodulin, osteopontin, and chitinase-3-like protein 1 significantly improves the ability to distinguish between good and poor transplant outcomes. This suggests that integrating these biomarkers into the kidney transplant allocation process could provide better insights into donor organ quality.