Novel and High-Throughput Method of Isolating Single Fetal Cells Using FACS for NIPT
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The authors aimed to evaluate the efficacy of fluorescence activated cell sorting (FACS) for isolating rare circulating fetal cells from maternal blood to enhance cell-based non-invasive prenatal testing (cbNIPT). Their findings demonstrated that FACS can successfully isolate single fetal cells with a significant enrichment factor, enabling faster and high-throughput processing for genetic analysis. This method shows promise for improving the accuracy and efficiency of prenatal genetic testing.
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