Comparative effectiveness of 200mcg versus 400mcg misoprostol dosing for medication abortion from 24-27 weeks' gestation
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The authors aimed to compare the effectiveness and adverse outcomes of two dosing regimens of misoprostol (200mcg vs. 400mcg) for medication abortion between 24-27 weeks' gestation. Their retrospective cohort study found that while both dosing regimens resulted in similar overall outcomes, the 200mcg group showed a trend towards longer time to placental expulsion and higher rates of complications, suggesting the need for larger studies to determine the optimal dosing.
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