July 1, 2026 · BMJ (Clinical research ed.) · DOI: 10.1136/bmj-2026-319692

Robotic versus Open Pancreatoduodenectomy (PORTAL): multicentre, single masked, phase 3, non-inferiority randomised controlled trial

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The study aimed to determine whether robotic pancreatoduodenectomy (RPD) is non-inferior to open pancreatoduodenectomy (OPD) regarding postoperative functional recovery, safety, and oncological quality. Results indicated that RPD significantly improved recovery time compared to OPD while maintaining comparable postoperative morbidity and mortality rates, although it incurred higher hospital admission costs. The findings suggest that RPD can be a viable alternative to OPD in high-volume centers with experienced surgeons.

Jiabin Jin, Kai Qin, Georgios Gemenetzis, Zheng Wang, Chenxi Zheng, Wei Li, Zehua Wu, Yusheng Shi, Mengmin Chen, Jianfeng Qian, Yuanchi Weng, Wei Chen, Weiwei Jin, Renan Jin, Jian Li, Leshan Liu, Yuntao Chen, Bing Han, Xiao Liang, Chuandong Sun, Zheng Wu, Yiping Mou, Xiaoyu Yin, Xiaxing Deng, Chenghong Peng, Tianlin He, Yanyan Song, Baiyong Shen

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