June 19, 2026 · Clinical radiology · DOI: 10.1016/j.crad.2026.107395

Automated computed tomography (CT) perfusion in the assessment of the ischaemic core in wake-up strokes: is it reliable?

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The authors aimed to evaluate the reliability of computed tomography perfusion (CTP) in assessing the ischaemic core in patients with wake-up strokes. Their findings indicate that CTP alone is not a reliable method, as it underestimated the ischaemic core in 38% of cases compared to non-contrast CT, suggesting that both imaging techniques should be used together to accurately determine thrombectomy eligibility in this patient population.

J-M U-King-Im, N Kallam, J Chandra, J Patel, A Al Busaidi, Y H Mah, J Teo, T Booth

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